A computational model of bleb formation
نویسندگان
چکیده
منابع مشابه
A computational model of bleb formation.
Blebbing occurs when the cytoskeleton detaches from the cell membrane, resulting in the pressure-driven flow of cytosol towards the area of detachment and the local expansion of the cell membrane. Recent interest has focused on cells that use blebbing for migrating through 3D fibrous matrices. In particular, metastatic cancer cells have been shown to use blebs for motility. A dynamic computatio...
متن کاملComputational fluid dynamic analysis of intracranial aneurysmal bleb formation.
BACKGROUND The management of unruptured aneurysms is controversial, with the decision to treat influenced by aneurysm characteristics including size and morphology. Aneurysmal bleb formation is thought to be associated with an increased risk of rupture. OBJECTIVE To correlate computational fluid dynamic (CFD) indices with bleb formation. METHODS Anatomic models were constructed from 3-dimen...
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deployable scissor type structures are composed of the so-called scissor-like elements (sles), which are connected to each other at an intermediate point through a pivotal connection and allow them to be folded into a compact bundle for storage or transport. several sles are connected to each other in order to form units with regular polygonal plan views. the sides and radii of the polygons are...
Hemodynamics and bleb formation in intracranial aneurysms.
BACKGROUND AND PURPOSE Intracranial aneurysms with irregular shapes and blebs or secondary outpouchings have been correlated with increased rupture risk. The purpose of this study was to investigate possible associations between the local hemodynamics and the formation of blebs in cerebral aneurysms. MATERIALS AND METHODS Computational models of 20 cerebral aneurysms harboring 30 well-defined...
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ژورنال
عنوان ژورنال: Mathematical Medicine and Biology
سال: 2012
ISSN: 1477-8599,1477-8602
DOI: 10.1093/imammb/dqr030